Neuropeptide Y (3-36) (porcine) 

Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36^[1][2][3].

Neuropeptide Y (3-36) (porcine) accounts for 35% of NPY-like immunoreactivity in porcine brain^[2].
  Neuropeptide Y (3-36) (porcine) shows high affinity for Y2-like receptors on CHP234 cells, and light affinity Y1-like receptors on SK-N-MC cells^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Neuropeptide Y (3-36) (porcine) (0.24-24 nM; i.c.v.; single dose) induces feeding in the rat in a dose-dependent manner^[1].
Neuropeptide Y (3-36) (porcine) (4 μg, 8 μg; i.c.v.; single dose) significantly increased food intake at 2 and 3 h, results dose-dependently orexigenic effect in rainbow trout (Oncorhynchus mykiss)^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

3993.36

C₁₇₆H₂₇₁N₅₃O₅₄

143863-88-1

SKPDNPGEDAPAEDLARYYSALRHYINLITRQRY-NH2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. O'Shea D, et al. Neuropeptide Y induced feeding in the rat is mediated by a novel receptor. Endocrinology. 1997 Jan;138(1):196-202.  [Content Brief]

  [2]. Grandt D, et al. Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors. Regul Pept. 1996 Nov 14;67(1):33-7.  [Content Brief]

  [3]. M Aldegunde, et al. Effects of neuropeptide Y on food intake and brain biogenic amines in the rainbow trout (Oncorhynchus mykiss), Peptides. 2006; 27(4):719-727.  [Content Brief]