2. GPCR/G Protein
  3. Succinate Receptor 1
  4. NF-56-EJ40 hydrochloride

NF-56-EJ40 hydrochloride 是一种有效，高亲和力和高度选择性的人 SUCNR1 (GPR91) 拮抗剂，IC50 为 25 nM，Ki 为 33.5 nM，对大鼠 SUCNR1 几乎没有活性。 NF-56-EJ40 hydrochloride 对人源化大鼠 SUCNR1 具有高亲和力，Ki 值为 17.4 nM。

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NF-56-EJ40 hydrochloride Chemical Structure

NF-56-EJ40 hydrochloride Chemical Structure

CAS No. : 2728500-80-7

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NF-56-EJ40 hydrochloride 的其他形式现货产品:

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NF-56-EJ40 hydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 hydrochloride has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM[1].

分子量

516.46

Formula

C27H31Cl2N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NF-56-EJ40 hydrochloride 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NF-56-EJ402728500-80-7Succinate Receptor 1SUCNR1GPR91Inhibitorinhibitorinhibit

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产品名称：
NF-56-EJ40 hydrochloride
目录号：
HY-130246A
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