1. PROTAC
  2. PROTAC Linkers
  3. Nonaethylene glycol monomethyl ether

Nonaethylene glycol monomethyl ether 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

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Nonaethylene glycol monomethyl ether Chemical Structure

Nonaethylene glycol monomethyl ether Chemical Structure

CAS No. : 6048-68-6

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1 g ¥100
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5 g ¥400
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10 g ¥758
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25 g ¥1804
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100 g ¥5952
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生物活性

Nonaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

428.51

Formula

C19H40O10

CAS 号
性状

<14°C 固体,>14°C 液体

颜色

Colorless to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Nonaethylene glycol monomethyl ether 相关分类

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Nonaethylene glycol monomethyl ether
目录号:
HY-120175
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