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  4. NSC363998 free base

NSC363998 (free base) 是一种化合物，具有口服活性。NSC363998 (free base) 可以抑制 rCGG90 诱导的神经毒性。NSC363998 (free base) 可用于神经退行性疾病的研究，如脆性 X 相关震颤/共济失调综合征 (FXTAS)。

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NSC363998 free base Chemical Structure

NSC363998 free base Chemical Structure

CAS No. : 159357-82-1

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NSC363998 free base 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS)[1].

体内研究
(In Vivo)

NSC363998 (free base) (oral; 0, 5 μM) can suppress rCGG90 induced neurotoxicity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: FXTAS Drosophila model[1]
Dosage: 0, 5 μM
Administration: Oral (dissolved in DMSO and added to standard food)
Result: Could modify ommatidial degeneration and diminished neddylation activity in the FXTAS Drosophila model.
分子量

440.54

Formula

C24H32N4O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NSC363998 free base 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSC363998159357-82-1NSC 363998NSC-363998OthersoralrCGG90neurotoxicityneurodegenerative disorderFragile X associated tremor/ataxia syndrome (FXTAS)Inhibitorinhibitorinhibit

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