2. Metabolic Enzyme/Protease
  3. Dipeptidyl Peptidase
  4. NVP-DPP728

NVP-DPP728 是一种有效、可逆、腈依赖性二肽基肽酶 IV (DPP-IV) 抑制剂。NVP-DPP728 可以抑制人 DPP-IV 的酰胺溶酶活性，Ki 为 11 nM。NVP-DPP728 可抑制胰高血糖素样肽-1 (GLP-1)的降解，从而增强胰岛素对葡萄糖摄入的释放。NVP-DPP728 可用于糖尿病研究。

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NVP-DPP728 Chemical Structure

NVP-DPP728 Chemical Structure

CAS No. : 247016-69-9

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

Other Forms of NVP-DPP728:

NVP-DPP728 相关抗体

Top Publications Citing Use of Products

查看 Dipeptidyl Peptidase 亚型特异性产品:

查看所有亚型
DPP-1 DPP-2 DPP-4 DPP-8 DPP-9

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NVP-DPP728 is a potent, reversible and nitrile-dependent dipeptidyl peptidase IV (DPP-IV) inhibitor. NVP-DPP728 can inhibit human DPP-IV amidolytic activity with a Ki of 11 nM. NVP-DPP728 inhibits degradation of glucagon-like peptide-1 (GLP-1) and thereby potentiates insulin release in response to glucose intake. NVP-DPP728 can be used for researching diabetes[1].

IC50 & Target

Ki: 11 nM (DPP-IV)[1]
分子量

298.34

Formula

C15H18N6O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NVP-DPP728 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NVP-DPP728247016-69-9Dipeptidyl PeptidaseDPPDipeptidyl peptidase IVGlucagonInsulinDiabetesReversibleInhibitorinhibitorinhibit

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产品名称：
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目录号：
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