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o,p'-DDE  (Synonyms: 2,4'-DDE; 2,4-Dichlorodiphenyldichloroethylene; 2,4'-DDE; o,p'-Dichlorodiphenyldichloroethylene)

目录号: HY-121779
产品使用指南

o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) 是有机氯农药 DDT 的代谢物和降解产物。它会在小口水牛、沟鲶和大口鲈鱼体内积聚,也会在亨茨维尔泉支-印第安溪支流系统周围的 DDT 制造厂沉积物中积聚,并在那里被视为持久性有机污染物 (POP)。o,p'-DDE 可抑制雌激素与虹鳟雌激素受体 (rtER) 的结合,IC50 值为 3.2 μM。它会诱导从猪卵泡中分离的颗粒细胞和卵泡膜细胞共培养物产生浓度依赖性的雌二醇分泌。卵内暴露于 o,p'-DDE 会增加日本青鳉 (O. latipes) 的卵泡退化并减小睾丸尺寸。

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o,p'-DDE Chemical Structure

o,p'-DDE Chemical Structure

CAS No. : 3424-82-6

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Other Forms of o,p'-DDE:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass, and in sediments from DDT manufacturing plants around the Huntsville Spring Branch-Indian Creek tributary system, where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to the rainbow trout estrogen receptor (rtER) with an IC50 value of 3.2 μM. It induces concentration-dependent estradiol secretion in co-cultures of granulosa and theca cells isolated from porcine follicles. In ovo exposure to o,p'-DDE increases follicular degeneration and reduces testis size in Japanese medaka (O. latipes).

分子量

318.03

Formula

C14H8Cl4

CAS 号
中文名称

2,4′-DDE 溶液

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

o,p'-DDE 相关分类

  • 摩尔计算器

  • 稀释计算器

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o,p'-DDE
目录号:
HY-121779
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