1. Apoptosis
  2. TNF Receptor
  3. Onfekafusp alfa

Onfekafusp alfa  (Synonyms: L19TNF)

目录号: HY-P99772

Onfekafusp alfa (L19TNF) 是一种同源三聚体,由 L19 抗体的工程肽以 scFv 形式与人 TNF 融合形成。Onfekafusp alfa 可用于恶性胶质瘤研究。

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CAS No. : 1957239-88-1

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  • 生物活性

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生物活性

Onfekafusp alfa (L19TNF) is a homotrimer that forms from engineered peptides for the L19 antibody in scFv format fused to human TNF. Onfekafusp alfa can be used for malignant glioma research[1][2].

同型

[scFv-heavy-kappa]-trimer

种属

Human

体外研究
(In Vitro)

Onfekafusp alfa 显示出比 mTNFα 和 TN11mTNFα 更强的抗癌活性[2]
在 L-M 小鼠成纤维细胞的细胞毒性试验中,Onfekafusp alfa 的活性比等摩尔量的重组 mTNFα 和融合蛋白 TN11mTNFα 高 5 到 6 倍[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 号
储存方式

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Format
  • [scFv-heavy-kappa]-trimer
纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Onfekafusp alfa
目录号:
HY-P99772
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