1. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  2. EGFR
  3. Osimertinib mesylate (Standard)

Osimertinib mesylate (Standard)  (Synonyms: 奥希替尼甲磺酸盐(Standard))

目录号: HY-15772AR 纯度: ≥98%
产品使用指南

Osimertinib (mesylate) (Standard)是 Osimertinib (mesylate) 的分析标准品。本产品用于研究及分析应用。Osimertinib mesylate (AZD-9291 mesylate) 是不可逆的突变体选择性 EGFR 抑制剂;对EGFRL858R 和EGFRL858R/T790MIC50 值分别为12 和 1 nM。

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Osimertinib mesylate (Standard) Chemical Structure

Osimertinib mesylate (Standard) Chemical Structure

CAS No. : 1421373-66-1

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  • 产品信息

  • 纯度 & 产品资料

生物活性

Osimertinib (mesylate) (Standard) is the analytical standard of Osimertinib (mesylate). This product is intended for research and analytical applications. Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.

分子量

595.71

Formula

C29H37N7O5S

CAS 号
中文名称

奥斯替尼甲磺酸盐(Standard);奥希替尼甲磺酸盐(Standard)

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Osimertinib mesylate (Standard)
目录号:
HY-15772AR
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