2. NF-κB
  3. NF-κB
  4. OT-551

OT-551 是一种 NF-κB 抑制剂，具有抗氧化和抗炎作用。OT-551 具有用于视网膜疾病研究的潜力。

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OT-551 Chemical Structure

OT-551 Chemical Structure

CAS No. : 627085-15-8

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规格 是否有货
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OT-551 相关抗体

Top Publications Citing Use of Products

查看 NF-κB 亚型特异性产品:

查看所有亚型
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

OT-551 is a NF-κB inhibitor with antioxidant and anti-inflammatory effects. OT-551 has the potential for retinal diseases research[1][2].

体内研究
(In Vivo)

OT-551（25-100 mg/kg；腹腔注射；一次）为白化大鼠提供 RPE 细胞保护，防止急性光损伤[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley (SD) albino rats (6-7 weeks of age) exposure to 2700 lux white fluorescent light[1]
Dosage: 25, 50, or 100 mg/kg
Administration: ip; once
Result: Retinal pigment epithelium (RPE) damage index was significantly lower in the animals.
分子量

277.79

Formula

C13H24ClNO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

OT-551 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OT-551627085-15-8OT551OT 551NF-κBNuclear factor-κBNuclear factor-kappaBNF-κB inhibitorantioxidantanti-inflammatory effectsretinal diseasesInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-W556870
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