2. Apoptosis
  3. Apoptosis
  4. Pancratistatin

Pancratistatin  (Synonyms: (+)-Pancratistatin)

目录号: HY-102010
产品使用指南 技术支持

Pancratistatin 是一种异喹啉生物碱，可以从蜘蛛兰 Hymenocallis littoralis 中分离。Pancratistatin 诱导人黑素瘤细胞凋亡。Pancratistatin 可用于神经母细胞瘤、白血病、和乳腺癌的研究。

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Pancratistatin Chemical Structure

Pancratistatin Chemical Structure

CAS No. : 96203-70-2

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规格 价格 是否有货 数量
1 mg ￥7000
1 - 2 周
5 mg   询价  
10 mg   询价  

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Customer Review

Pancratistatin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pancratistatin is an isoquinoline alkaloid that can be isolated from Hymenocallis littoralis. Pancratistatin induces apoptosis of human melanoma cells. Pancratistatin can be used for the research of neuroblastoma, leukemia and breast cancer[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
BXPC-3 GI50
0.02 μg/mL
Compound: 1a
Cytotoxicity against human BxPC3 cells after 48 hrs by SRB assay
Cytotoxicity against human BxPC3 cells after 48 hrs by SRB assay
[PMID: 22413911]
BXPC-3 ED50
0.02 μg/mL
Compound: 1
Growth inhibition of human BXPC3 cells after 48 hrs
Growth inhibition of human BXPC3 cells after 48 hrs
[PMID: 17346078]
BXPC-3 ED50
0.043 μg/mL
Compound: 1
Cytotoxicity against human BxPC3 cells after 48 hrs by SRB assay
Cytotoxicity against human BxPC3 cells after 48 hrs by SRB assay
[PMID: 16124772]
DU-145 GI50
0.015 μg/mL
Compound: 1a
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
[PMID: 22413911]
DU-145 GI50
0.015 μg/mL
Compound: 1
Growth inhibition of human DU145 cells after 48 hrs
Growth inhibition of human DU145 cells after 48 hrs
[PMID: 17346078]
DU-145 ED50
0.037 μg/mL
Compound: 1
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells after 48 hrs by SRB assay
[PMID: 16124772]
KM-20L2 GI50
0.025 μg/mL
Compound: 1a
Cytotoxicity against human KM20L2 cells after 48 hrs by SRB assay
Cytotoxicity against human KM20L2 cells after 48 hrs by SRB assay
[PMID: 22413911]
KM-20L2 GI50
0.025 μg/mL
Compound: 1
Growth inhibition of human KM20L2 cells after 48 hrs
Growth inhibition of human KM20L2 cells after 48 hrs
[PMID: 17346078]
KM-20L2 ED50
0.048 μg/mL
Compound: 1
Cytotoxicity against human KM20L2 cells after 48 hrs by SRB assay
Cytotoxicity against human KM20L2 cells after 48 hrs by SRB assay
[PMID: 16124772]
MCF7 GI50
0.023 μg/mL
Compound: 1a
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
[PMID: 22413911]
MCF7 ED50
0.023 μg/mL
Compound: 1
Growth inhibition of human MCF7 cells after 48 hrs
Growth inhibition of human MCF7 cells after 48 hrs
[PMID: 17346078]
MCF7 ED50
0.035 μg/mL
Compound: 1
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
[PMID: 16124772]
NCI-H460 ED50
0.029 μg/mL
Compound: 1
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
[PMID: 16124772]
NCI-H460 GI50
0.032 μg/mL
Compound: 1a
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
[PMID: 22413911]
NCI-H460 GI50
0.032 μg/mL
Compound: 1
Growth inhibition of human NCI-H460 cells after 48 hrs
Growth inhibition of human NCI-H460 cells after 48 hrs
[PMID: 17346078]
P388 ED50
0.017 μg/mL
Compound: 1a
Cytotoxicity against mouse P388 cells after 48 hrs by cell counting
Cytotoxicity against mouse P388 cells after 48 hrs by cell counting
[PMID: 22413911]
P388 ED50
0.017 μg/mL
Compound: 1
Growth inhibition of murine P388 cells after 48 hrs
Growth inhibition of murine P388 cells after 48 hrs
[PMID: 17346078]
SF-268 GI50
0.014 μg/mL
Compound: 1a
Cytotoxicity against human SF268 cells after 48 hrs by SRB assay
Cytotoxicity against human SF268 cells after 48 hrs by SRB assay
[PMID: 22413911]
SF-268 GI50
0.014 μg/mL
Compound: 1
Growth inhibition of human SF268 cells after 48 hrs
Growth inhibition of human SF268 cells after 48 hrs
[PMID: 17346078]
SF-268 ED50
0.032 μg/mL
Compound: 1
Cytotoxicity against human SF268 cells after 48 hrs by SRB assay
Cytotoxicity against human SF268 cells after 48 hrs by SRB assay
[PMID: 16124772]
Vero IC50
0.016 μg/mL
Compound: 4
Antiviral activity against Yellow fever virus Ashibi infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
Antiviral activity against Yellow fever virus Ashibi infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
[PMID: 1336040]
Vero IC50
0.022 μg/mL
Compound: 4
Antiviral activity against Japanese encephalitis virus Nakayama infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
Antiviral activity against Japanese encephalitis virus Nakayama infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
[PMID: 1336040]
Vero IC50
0.063 μg/mL
Compound: 4
Antiviral activity against Dengue virus type 4 infected in african green monkey Vero cells after 6 days by plaque reduction assay
Antiviral activity against Dengue virus type 4 infected in african green monkey Vero cells after 6 days by plaque reduction assay
[PMID: 1336040]
Vero IC50
0.16 μg/mL
Compound: 4
Antiviral activity against Rift Valley fever virus infected in african green monkey Vero cells after 6 days by plaque reduction assay
Antiviral activity against Rift Valley fever virus infected in african green monkey Vero cells after 6 days by plaque reduction assay
[PMID: 1336040]
分子量

325.27

Formula

C14H15NO8
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pancratistatin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pancratistatin96203-70-2(+)-PancratistatinApoptosisalkaloidHymenocallis littoralisapoptosisneuroblastomaleukemiabreast cancerInhibitorinhibitorinhibit

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