2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. PD 121373

PD 121373 是一种 DNA 络合剂，具有抗肿瘤活性。PD 121373 能够与 DNA 和 RNA 紧密结合，并抑制 DNA 和 RNA 的合成。PD 121373 抑制 L1210 细胞中 DNA 和 RNA 合成的 IC50 值分别为 0.5 μM 和 0.3 μM。

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PD 121373 Chemical Structure

PD 121373 Chemical Structure

CAS No. : 113457-06-0

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PD 121373 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PD 121373 is a DNA complexing agent with antitumor activity. PD 121373 can bind tightly to DNA and RNA and inhibit the synthesis of DNA and RNA. The IC50 values ??of PD 121373 for inhibiting DNA and RNA synthesis in L1210 cells are 0.5 μM and 0.3 μM, respectively[1].

分子量

397.54

Formula

C21H27N5OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PD 121373 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PD 121373113457-06-0PD121373PD-121373DNA/RNA SynthesisComplexing agentanti-tumorDNARNAL1210 cellsInhibitorinhibitorinhibit

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