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  3. PDHK-IN-7

PDHK-IN-7 (compound 32) 是丙酮酸脱氢酶激酶的抑制剂,其IC50值为 17 nM。PDHK-IN-7 可激活大鼠肝脏中的 PDH,并对 Zucker 肥胖大鼠具有降糖作用。

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PDHK-IN-7 Chemical Structure

PDHK-IN-7 Chemical Structure

CAS No. : 1220965-73-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PDHK-IN-7 (compound 32) is an inhibitor of pyruvate dehydrogenase kinase with an IC50 value of 17 nM.PDHK-IN-7 activates PDH in rat livers and has a glucose-lowering effect in Zucker fatty rats[1].

分子量

374.36

Formula

C20H17F3N2O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PDHK-IN-7
目录号:
HY-162586
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