2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. Pepinh-TRIF TFA

Pepinh-TRIF (TFA) 是一种 30 aa 肽，通过干扰 TLR-TRIF 的相互作用 (TLR-TRIF interaction ) 来阻断 TRIF 信号。

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Custom Peptide Synthesis

Pepinh-TRIF TFA Chemical Structure

Pepinh-TRIF TFA Chemical Structure

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货
1 mg ￥1600
询问价格 & 货期
5 mg ￥3700
询问价格 & 货期
10 mg ￥5900
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Customer Review

Pepinh-TRIF TFA 相关抗体

Top Publications Citing Use of Products

查看 Toll-like Receptor (TLR) 亚型特异性产品:

查看所有亚型
TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pepinh-TRIF (TFA) is a 30 aa peptide that blocks TIR-domain-containing adapter-inducing interferon-β (TRIF) signaling by interfering with TLR-TRIF interaction[1].

IC50 & Target

TLRs

 

体外研究
(In Vitro)

Pepinh-TRIF (40 μM，6 小时) 阻断 polyI:C 或鞭毛蛋白刺激的 IL-33 的表达和产生，并极大地抑制 HCECs 中刺激的 IκB-α 磷酸化和降解[1]。
Pepinh-TRIF (40 μM，6 小时) 通过 p65 蛋白核转位抑制 NF-κB 激活[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pepinh-TRIF TFA 相关抗体:

Western Blot Analysis[1]

Cell Line: HCECs
Concentration: 40 μM
Incubation Time: 6 hours
Result: Blocked NF-κB activation with p65 nuclear translocation.
分子量

4016.63

Formula

C180H279F3N58O40S2
性状

固体

颜色

White to off-white

Sequence Shortening

RQIKIWFQNRRMKWKKFCEEFQVPGRGELH-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

纯度 & 产品资料
参考文献

Pepinh-TRIF TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pepinh-TRIFToll-like Receptor (TLR)peptideTRIFTIR-domain-containingadapter-inducinginterferon-βTLRtoll-likereceptorInhibitorinhibitorinhibit

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产品名称：
Pepinh-TRIF TFA
目录号：
HY-P2565
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