1. GPCR/G Protein Neuronal Signaling
  2. Neuropeptide Y Receptor
  3. Peptide YY (pig)

Peptide YY (pig) 是一种长 36 个氨基酸的胃肠肽,可从猪十二指肠分离得到。Peptide YY (pig) 能够激活 Y2 receptor,以降低食欲和食物摄入量。Peptide YY (pig) 主要存在于胰腺内分泌细胞中,对肠动力和心血管系统都有影响。

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Custom Peptide Synthesis

Peptide YY (pig) Chemical Structure

Peptide YY (pig) Chemical Structure

CAS No. : 81858-94-8

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查看 Neuropeptide Y Receptor 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Peptide YY (pig) is a 36 amino acid gastrointestinal peptide, can be isolated from porcine duodenum. Peptide YY (pig) decreases appetite and food-intake by activation of the Y2 receptor. Peptide YY (pig) is present mainly in pancreatic endocrine cells with effect on both intestinal motility and the cardiovascular system[1][2][3].

IC50 & Target[3]

NPY Y2 receptor

 

体外研究
(In Vitro)

Peptide YY (pig) (10 μg/mL) 和人类胰多肽 (PP) 一样具有抗体特异性,即对 PYY 抗血清特异,两者都可能在各种脊椎动物胰岛激素分泌的调节中发挥内分泌或旁分泌作用[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Peptide YY1-36 (pig) 会被二肽基肽酶 IV (DPP-IV) 降解为 PYY3-36。PYY3-36 (50 nmol/kg; 静脉注射; 单剂量) 在哥根廷迷你猪和恒河猴中会进一步分解为许多代谢产物[3]
Peptide YY1-36 (pig) 具有减缓肠道转运、抑制胃肠道负离子和电解质分泌、降低血糖等其他生理作用[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

4240.72

Formula

C190H288N54O57

CAS 号
Sequence Shortening

YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Peptide YY (pig)
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HY-P2703
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