2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Piroxantrone

Piroxantrone  (Synonyms: Oxantrazole; NCS 349174)

目录号: HY-13726
产品使用指南

摩尔计算器

Piroxantrone (Oxantrazole) 是一种有效的靶向 DNA 拓扑异构酶 II 的蒽吡唑类抗肿瘤剂。Piroxantrone 具有心脏毒性。

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Piroxantrone Chemical Structure

Piroxantrone Chemical Structure

CAS No. : 91441-23-5

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Piroxantrone 相关抗体

Top Publications Citing Use of Products

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Topoisomerase Topo I Topo II

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Piroxantrone (Oxantrazole) is a potent DNA topoisomerase II-targeting anthrapyrazole antitumor agent. Piroxantrone displays cardiotoxicity[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
K562 IC50
4 μM
Compound: Piroxantrone
Growth inhibition of human K562 cells after 72 hrs by MTS method
Growth inhibition of human K562 cells after 72 hrs by MTS method
[PMID: 18258442]
分子量

411.45

Formula

C21H25N5O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Piroxantrone 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Piroxantrone91441-23-5Oxantrazole NCS 349174NCS349174NCS 349174NCS-349174TopoisomeraseAntitumorcardiotoxicityInhibitorinhibitorinhibit

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