2. Metabolic Enzyme/Protease
  3. Apolipoprotein
  4. Plozasiran

Plozasiran  (Synonyms: ARO-APOC3)

目录号: HY-164740
产品使用指南

摩尔计算器

Plozasiran 是一种靶向 APOC3 的 siRNA，用于混合型高脂血症的研究。

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RNA, ([1'-de(6-amino-9H-purin-9-yl)]dA-(5'→5')-sp-Am-Cm-Gm-Gm-Gm-Am-Cm-Am- (2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-Um-Um-Cm-Um-CmAm-Gm-Um-Im-Am-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]dA), 3'-[O-[cis-4- [(3S,8S)-17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,8-bis[[[2-[2-[[2- (acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]amino]carbonyl]- 1,6,11-trioxo-15-oxa-2,7,12-triazaheptadec-1-yl]cyclohexyl] hydrogen phosphorothioate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)C-sp-Am-sp-(2'- deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Am-Gm-Am-Am-Um-(2'-deoxy-2'- fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)CCm-(2'-deoxy-2'-fluoro)G-sp-Um) (1:1)

Plozasiran Chemical Structure

CAS No. : 2379776-40-4

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Plozasiran 相关抗体

Top Publications Citing Use of Products

查看 Apolipoprotein 亚型特异性产品:

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apoC3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Plozasiran is an siRNA targeting APOC3 for the study of mixed hyperlipidemia.

IC50 & Target

apoC3

 

分子量

15618.77

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Plozasiran 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Plozasiran2379776-40-4ARO-APOC3ApolipoproteinInhibitorinhibitorinhibit

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