1. Stem Cell/Wnt TGF-beta/Smad
  2. TGF-beta/Smad TGF-β Receptor
  3. (+)-ITD-1

(+)-ITD-1 是 TGF-β 的抑制剂,可以抑制 TGF-β2IC50 为 0.46 μM。(+)-ITD-1 促进 TGF-β II 型受体(TGFBR2)的降解和心肌细胞的分化,并在小鼠胚胎干细胞(mESCs)分化早期抑制中胚层的形成。

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(+)-ITD-1 Chemical Structure

(+)-ITD-1 Chemical Structure

CAS No. : 1409968-46-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(+)-ITD-1 is an inhibitor for TGF-β, that inhibits the TGF-β2 with an IC50 of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte, and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs)[1].

分子量

415.52

Formula

C27H29NO3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(+)-ITD-1
目录号:
HY-137063
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