1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. PMEG-DP disodium

PMEG-DP disodium 是一种有效的 DNA 聚合酶 抑制剂 (IC50=2.5 μM),特别是对 DNA 聚合酶 αδ 具有强大的抑制作用。PMEG-DP disodium 作为 G-9191 的活性代谢物,GS-9191 能有效抑制乳头状瘤病毒 (HPV) 感染的细胞系生长。PMEG-DP disodium 可用于在 HPV 相关疾病的研究。

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PMEG-DP disodium Chemical Structure

PMEG-DP disodium Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PMEG-DP disodium is a potent DNA polymerase inhibitor (IC50=2.5 μM), especially for DNA polymerase α and δ. PMEG-DP disodium acts as an active metabolite of G-9191, which effectively inhibits the growth of papillomavirus (HPV) -infected cell lines. PMEG-DP disodium can be used in the study of HPV-related diseases[1].

分子量

493.11

Formula

C8H12N5Na2O11P3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

PMEG-DP disodium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PMEG-DP disodium
目录号:
HY-164018A
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