2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. PNU-22394 hydrochloride

PNU-22394 hydrochloride 是 5-HT 的激动剂，Ki 为 6.1 nM (5-HT2C) 和 10 nM (5-HT2A)。

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PNU-22394 hydrochloride Chemical Structure

PNU-22394 hydrochloride Chemical Structure

CAS No. : 15923-42-9

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PNU-22394 hydrochloride 相关抗体

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查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PNU-22394 hydrochloride is an agonist for 5-HT, with Ki of 6.1 and 10 nM, for 5-HT2C and 5-HT2A, respectively[1].

体内研究
(In Vivo)

PNU-22394 hydrochloride 是 5-HT2C and 5-HT2A 的激动剂，EC50 的值根据测量方法的不同而出现差异 (通过 Fluo-4/Ca2+ 测定法测量为 7.7 和 23 nM；通过 IP-One 测定法测量为 0.12 和 0.21 μM)， Rmax 为 97%-102%[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

236.74

Formula

C13H17ClN2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PNU-22394 hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

PNU-2239415923-42-9PNU22394PNU 223945-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorHEK293Inhibitorinhibitorinhibit

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目录号：
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