2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. Pomaglumetad methionil

Pomaglumetad methionil  (Synonyms: LY2140023 hydrate)

目录号: HY-105040
产品使用指南

摩尔计算器

Pomaglumetad methionil (LY2140023 hydrate) 是一种有效的特异性 mGlu2/3 受体激动剂 LY404039 (HY-50906) 的口服蛋氨酸前药。Pomaglumetad methionil 的耐受性良好，具有独特的安全性，可用于精神分裂症。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 Pomaglumetad methionil hydrochloride 通常具有更好的水溶性和稳定性。

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Pomaglumetad methionil Chemical Structure

Pomaglumetad methionil Chemical Structure

CAS No. : 956385-05-0

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Pomaglumetad methionil 的其他形式现货产品:

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Other Forms of Pomaglumetad methionil:

Pomaglumetad methionil 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pomaglumetad methionil (LY2140023 hydrate) is an oral methionine prodrug of the potent specific mGlu2/3 receptor agonist LY404039 (HY-50906). Pomaglumetad methionil is well-tolerated and has a distinct safety profile, and can be used for schizophrenia[1][2].

IC50 & Target[1][2]

mGluR2

 

mGluR3

 

Clinical Trial
分子量

384.43

Formula

C12H20N2O8S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pomaglumetad methionil 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomaglumetad methionil956385-05-0LY2140023LY 2140023LY-2140023mGluRMetabotropic glutamate receptorsLY404039methionineprodrugwell-toleratedsafetyschizophreniaInhibitorinhibitorinhibit

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