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Porfimer sodium  (Synonyms: Photofrin II)

目录号: HY-156787
产品使用指南

Porfimer sodium (Photofrin II)是一种具有光敏活性的化合物,主要用于光动力抑制。Porfimer sodium被肿瘤细胞选择性吸收,激活后能产生氧自由基。Porfimer sodium在细胞内引起Ca(2+)浓度的变化,表现出急性电生理反应和细胞形态的改变。Porfimer sodium的应用可以导致细胞膜表面微孔的形成,从而导致坏死性细胞死亡。

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Porfimer sodium Chemical Structure

Porfimer sodium Chemical Structure

CAS No. : 87806-31-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Porfimer sodium (Photofrin II) is a photosensitizing compound used primarily for photodynamic inhibition. Porfimer sodium is selectively taken up by tumor cells and can generate oxygen free radicals upon activation. Porfimer sodium causes changes in Ca(2+) concentrations within cells, exhibiting acute electrophysiological responses and changes in cell morphology. The application of porfimer sodium can lead to the formation of micropores on the cell membrane surface, resulting in necrotic cell death[1].

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Porfimer sodium 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Porfimer sodium
目录号:
HY-156787
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