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  3. Poricoic acid G

Poricoic acid G  (Synonyms: 茯苓酸G)

目录号: HY-N10071
产品使用指南

Poricoic acid G 是一种可以从 Poria cocos 中分离得到的三萜化合物。Poricoic acid G 对白血病细胞具有显著的细胞毒性作用,是一种潜在的有效的抗人白血病化合物。

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Poricoic acid G Chemical Structure

Poricoic acid G Chemical Structure

CAS No. : 415724-84-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Poricoic acid G is a triterpenoid that can be isolated from Poria cocos. Poricoic acid G has a significant cytotoxic effect on leukemia cells and is a potential potent anti-leukemic compound in humans[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 100 μM
Compound: 3a
Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
AZ-521 cell line IC50
> 100 μM
Compound: 3a
Cytotoxicity in human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
DU-145 IC50
> 100 μM
Compound: 3a
Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
HL-60 IC50
32.6 μM
Compound: 3a
Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
HL-60 IC50
32.6 μM
Compound: 14
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
[PMID: 19746919]
HL-60 GI50
39.3 nM
Compound: 1, poricoic acid G
Growth inhibition of human HL60 cells after 48 hrs by sulforhodamine B assay
Growth inhibition of human HL60 cells after 48 hrs by sulforhodamine B assay
[PMID: 11975480]
OVCAR-3 IC50
> 100 μM
Compound: 3a
Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
PANC-1 IC50
> 100 μM
Compound: 3a
Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
SK-BR-3 IC50
> 100 μM
Compound: 3a
Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 21250700]
分子量

486.68

Formula

C30H46O5

CAS 号
结构分类
初始来源

Poria cocos

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Poricoic acid G
目录号:
HY-N10071
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