2. GPCR/G Protein Neuronal Signaling
  3. Neuropeptide Y Receptor
  4. (Pro34)-Peptide YY (human)

(Pro34)-Peptide YY (human) 是 Peptide YY (HY-P1514)/neuropeptide Y 受体的高度 Y1 选择性全激动剂。

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Custom Peptide Synthesis

(Pro34)-Peptide YY (human) Chemical Structure

(Pro34)-Peptide YY (human) Chemical Structure

CAS No. : 179986-93-7

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(Pro34)-Peptide YY (human) 相关抗体

Top Publications Citing Use of Products

查看 Neuropeptide Y Receptor 亚型特异性产品:

查看所有亚型
NPY Y1 receptor NPY Y2 receptor NPY Y4 receptor NPY Y5 receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(Pro34)-Peptide YY (human) is a highly Y1-selective full agonist of Peptide YY (HY-P1514)/neuropeptide Y receptors[1].

IC50 & Target[1]

NPY Y1 receptor

 

体外研究
(In Vitro)

(Pro34)-Peptide YY (human) 在完整的 SK-N-MC 和 HEL 细胞 (Y1 样亚型) 和猪脾膜 (Y2 样亚型) 中竞争所有特定的 [125I] 神经肽 Y 结合位点。(Pro34)-Peptide YY 在完整的 SK-N-MC 和 HEL 细胞中的亲和力 (pKi 分别为 7.8 ± 0.2 和 8.2 ± 0.1) 与 Peptide YY (pKi 分别为 8.5 ± 0.1 和 8.6 ± 0.1) 非常相似[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(Pro34)-Peptide YY (human) 相关抗体:
分子量

4278.73

Formula

C194H294N54O56
CAS 号
Sequence Shortening

YPIKPEAPGEDASPEELNRYYASLRHYLNLVTRPRY-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
细胞实验： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

(Pro34)-Peptide YY (human) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Pro34)-Peptide YY (human)179986-93-7Neuropeptide Y ReceptorNPY receptorSK-N-MCPeptide YYHELInhibitorinhibitorinhibit

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产品名称：
(Pro34)-Peptide YY (human)
目录号：
HY-P3876
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