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染色质免疫沉淀

染色质免疫沉淀 (Chromatin Immunoprecipitation, ChIP) 是一种用于研究蛋白与染色质相互作用的分子生物学技术。通过将某一蛋白抗体与染色质结合,然后通过沉淀该蛋白与其结合的染色质片段,ChIP 可以用于分析基因组中蛋白与 DNA 的相互作用、研究基因调控机制、以及探索表观遗传学等领域。ChIP 技术对于深入理解基因表达调控和细胞功能至关重要。


Chromatin Immunoprecipitation (ChIP) is a molecular biology technique used to study the interaction between proteins and chromatin. By binding a protein antibody to chromatin and then precipitating the chromatin fragments bound to the protein, ChIP can be used to analyze the interaction between proteins and DNA in the genome, study gene regulatory mechanisms, and explore epigenetics and other fields. . ChIP technology is essential for a deeper understanding of gene expression regulation and cellular function.