2. 天然产物
  3. 植物 生物碱
  4. 石蒜科 异喹啉类生物碱
  5. 水仙
  6. Pseudolycorine

Pseudolycorine  (Synonyms: 伪石蒜碱)

目录号: HY-117190
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Pseudolycorine 是一种具有抗癌活性的石蒜科生物碱。

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Pseudolycorine Chemical Structure

Pseudolycorine Chemical Structure

CAS No. : 29429-03-6

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Pseudolycorine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pseudolycorine is an Amaryllidaceae alkaloid with anticancer activity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
7.4 μM
Compound: 3
Cytotoxicity against human A549 cells after 72 hrs by MTT colorimetric assay
Cytotoxicity against human A549 cells after 72 hrs by MTT colorimetric assay
[PMID: 20550100]
A549 IC50
7.5 μM
Compound: 18, pseudolycorine
Growth inhibition of proapoptotic stimuli-resistant human A549 cells after 72 hrs by MTT assay
Growth inhibition of proapoptotic stimuli-resistant human A549 cells after 72 hrs by MTT assay
[PMID: 19788245]
B16-F10 IC50
7.5 μM
Compound: 18, pseudolycorine
Growth inhibition of proapoptotic stimuli-sensitive mouse B16F10 cells after 72 hrs by MTT assay
Growth inhibition of proapoptotic stimuli-sensitive mouse B16F10 cells after 72 hrs by MTT assay
[PMID: 19788245]
B16-F10 IC50
7.5 μM
Compound: 3
Cytotoxicity against mouse B16F10 cells after 72 hrs by MTT colorimetric assay
Cytotoxicity against mouse B16F10 cells after 72 hrs by MTT colorimetric assay
[PMID: 20550100]
Hs 683 IC50
7.9 μM
Compound: 18, pseudolycorine
Growth inhibition of proapoptotic stimuli-sensitive human Hs683 cells after 72 hrs by MTT assay
Growth inhibition of proapoptotic stimuli-sensitive human Hs683 cells after 72 hrs by MTT assay
[PMID: 19788245]
Hs 683 IC50
7.9 μM
Compound: 3
Cytotoxicity against human Hs683 cells after 72 hrs by MTT colorimetric assay
Cytotoxicity against human Hs683 cells after 72 hrs by MTT colorimetric assay
[PMID: 20550100]
NHDF IC50
66.9 μM
Compound: 18, pseudolycorine
Growth inhibition of human NHDF after 72 hrs by MTT assay
Growth inhibition of human NHDF after 72 hrs by MTT assay
[PMID: 19788245]
SK-MEL IC50
> 10 μM
Compound: 3
Cytotoxicity against human SK-MEL cells after 72 hrs by MTT colorimetric assay
Cytotoxicity against human SK-MEL cells after 72 hrs by MTT colorimetric assay
[PMID: 20550100]
SK-MEL-28 IC50
> 10 μM
Compound: 18, pseudolycorine
Growth inhibition of proapoptotic stimuli-resistant human SK-MEL-28 cells after 72 hrs by MTT assay
Growth inhibition of proapoptotic stimuli-resistant human SK-MEL-28 cells after 72 hrs by MTT assay
[PMID: 19788245]
U-373MG ATCC IC50
7.8 μM
Compound: 18, pseudolycorine
Growth inhibition of proapoptotic stimuli-resistant human U373 cells after 72 hrs by MTT assay
Growth inhibition of proapoptotic stimuli-resistant human U373 cells after 72 hrs by MTT assay
[PMID: 19788245]
U-373MG ATCC IC50
7.8 μM
Compound: 3
Cytotoxicity against human U373 cells after 72 hrs by MTT colorimetric assay
Cytotoxicity against human U373 cells after 72 hrs by MTT colorimetric assay
[PMID: 20550100]
Vero IC50
0.28 μg/mL
Compound: 17
Antiviral activity against Japanese encephalitis virus Nakayama infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
Antiviral activity against Japanese encephalitis virus Nakayama infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
[PMID: 1336040]
Vero IC50
0.35 μg/mL
Compound: 17
Antiviral activity against Yellow fever virus Ashibi infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
Antiviral activity against Yellow fever virus Ashibi infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
[PMID: 1336040]
Vero IC50
0.39 μg/mL
Compound: 17
Antiviral activity against Dengue virus type 4 infected in african green monkey Vero cells after 6 days by plaque reduction assay
Antiviral activity against Dengue virus type 4 infected in african green monkey Vero cells after 6 days by plaque reduction assay
[PMID: 1336040]
Vero IC50
0.6 μg/mL
Compound: 17
Antiviral activity against Punta Toro virus Adames infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
Antiviral activity against Punta Toro virus Adames infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay
[PMID: 1336040]
Vero IC50
0.63 μg/mL
Compound: 17
Antiviral activity against Rift Valley fever virus infected in african green monkey Vero cells after 6 days by plaque reduction assay
Antiviral activity against Rift Valley fever virus infected in african green monkey Vero cells after 6 days by plaque reduction assay
[PMID: 1336040]
WI-38 IC50
44 μM
Compound: 18, pseudolycorine
Growth inhibition of human WI38 cells after 72 hrs by MTT assay
Growth inhibition of human WI38 cells after 72 hrs by MTT assay
[PMID: 19788245]
体外研究
(In Vitro)

Pseudolycorine 显示出生长抑制活性，对 A549、OE21、Hs683、U373 和 B16F10 细胞的 IC50 值分别为 7.4 μM、7.9 μM、7.9 μM、7.8 μM 和 7.5 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pseudolycorine 相关抗体:
分子量

289.33

Formula

C16H19NO4
CAS 号
中文名称

伪石蒜碱
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pseudolycorine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pseudolycorine29429-03-6伪石蒜碱OthersAmaryllidaceae alkaloidanticancer activityInhibitorinhibitorinhibit

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