1. 生化试剂
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  3. PT-ttpy

Pt-ttpy 是一种金属有机复合物和有效的 G-四链体配体,它通过抑制端粒酶和/或端粒功能,有效地引发癌细胞中大量与端粒相关的 DNA 损伤,同时还在有丝分裂过程中引起各种染色质异常,例如染色质桥、超细桥 (UFB) 和双链断裂 (DSB)。

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PT-ttpy Chemical Structure

PT-ttpy Chemical Structure

CAS No. : 727721-37-1

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  • 生物活性

  • 纯度 & 产品资料

生物活性

Pt-ttpy, a metallo-organic complex and potent G-quadruplex ligand, effectively triggers substantial telomere-related DNA damage in cancer cells by inhibiting telomerase and/or telomere functions, while also causing various chromatin abnormalities during mitosis, such as chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs).

分子量

589.38

Formula

C22H17Cl2N3Pt

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PT-ttpy
目录号:
HY-W543137
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