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  4. Pyrrolidine ricinoleamide

Pyrrolidine ricinoleamide ((R)-5d) 是一种脂肪酸酰胺，对包括人类胶质瘤 U251 细胞在内的一系列癌细胞具有有效的抗增殖活性。Pyrrolidine ricinoleamide 可以用于癌症的研究。

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Pyrrolidine ricinoleamide Chemical Structure

Pyrrolidine ricinoleamide Chemical Structure

CAS No. : 1246776-23-7

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Pyrrolidine ricinoleamide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pyrrolidine ricinoleamide ((R)-5d) is a fatty acid amide that exhibits effective antiproliferative activity against a series of cancer cells, including human glioma U251 cells. Pyrrolidine ricinoleamide can be used in cancer research[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
786-0 GI50
4.1 μg/mL
Compound: (R)-5d
Antiproliferative activity against human 786-0 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human 786-0 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
MCF7 GI50
4.4 μg/mL
Compound: (R)-5d
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
NCI/ADR-RES GI50
4 μg/mL
Compound: (R)-5d
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
NCI-H460 GI50
6.9 μg/mL
Compound: (R)-5d
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
OVCAR-3 GI50
4.3 μg/mL
Compound: (R)-5d
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
PC-3 GI50
6.2 μg/mL
Compound: (R)-5d
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
U-251 GI50
1.5 μg/mL
Compound: (R)-5d
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
分子量

351.57

Formula

C22H41NO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pyrrolidine ricinoleamide 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyrrolidine ricinoleamide1246776-23-7OthersU251MCF-7NCI-ADR/RES786-0NCI-H460PC-3OVCAR-3cancerInhibitorinhibitorinhibit

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