2. Metabolic Enzyme/Protease
  3. Aminopeptidase
  4. QGC583

QGC583 是一种有效的选择性 Aminopeptidase A (APA) 抑制剂，具有口服活性和血脑屏障透过性，其 IC50 值为 4 nM。QGC583 可抑制大鼠的脑、肾和心脏的 APA 活性。

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QGC583 Chemical Structure

QGC583 Chemical Structure

CAS No. : 2417001-25-1

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QGC583 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

QGC583 is an effective selective Aminopeptidase A (APA) inhibitor with oral activity and blood-brain barrier permeability, boasting an IC50 value of 4 nM. QGC583 can inhibit APA activity in the brain, kidneys, and heart of rats[1].

IC50 & Target

IC50: 4 nM (APA)[1].
体内研究
(In Vivo)

QGC583 (2 mg/kg; i.v.; 单剂量) 降低大鼠心脏、肾脏和脑的 APA 活性，活性分别降低了 78% 、66% 和 71%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

301.28

Formula

C13H20NO5P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

QGC583 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

QGC5832417001-25-1QGC 583QGC-583AminopeptidaseSprague Dawley (SD) ratsInhibitorinhibitorinhibit

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目录号：
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