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(R)-Thionisoxetine hydrochloride  (Synonyms: LY-368975 hydrochloride)

目录号: HY-118064A
产品使用指南

(R)-Thionisoxetine hydrochloride (LY-368975 hydrochloride) 是一种有效的选择性中枢和外周去甲肾上腺素 (NE) 摄取抑制剂。(R)-Thionisoxetine hydrochloride 可防止 6-羟基多巴胺导致的下丘脑 NE 耗竭,ED50 为 0.21 mg/kg。(R)-Thionisoxetine hydrochloride 可用于多种疾病的研究,包括抑郁症和尿失禁。

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(R)-Thionisoxetine hydrochloride Chemical Structure

(R)-Thionisoxetine hydrochloride Chemical Structure

CAS No. : 222961-65-1

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  • 参考文献

生物活性

(R)-Thionisoxetine hydrochloride (LY-368975 hydrochloride) is a potent and selective central and peripheral norepinephrine (NE) uptake inhibitor. (R)-Thionisoxetine hydrochloride prevents 6-hydroxydopamine-induced hypothalamic NE depletion with an ED50 of 0.21 mg/kg. (R)-Thionisoxetine hydrochloride can be used in the study of a variety of diseases, including depression and urinary incontinence[1].

分子量

323.88

Formula

C17H22ClNOS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

(R)-Thionisoxetine hydrochloride 相关分类

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(R)-Thionisoxetine hydrochloride
目录号:
HY-118064A
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