1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. (Rac)-Beraprost sodium

(Rac)-Beraprost sodium  (Synonyms: 贝前列腺素钠; (Rac)-TRK-100; (Rac)-ML 1129 sodium)

目录号: HY-Z7721
产品使用指南

(Rac)-Beraprost ((Rac)-ML 1229) sodium 是 Beraprost sodium (HY-13569A) 的外消旋异构体。Beraprost sodium 是一种具有口服活性的前列环素类似物,通过与前列环素膜受体 (Prostaglandin Receptor) 结合来抑制 Ca2+ 从细胞内储存位点释放,从而导致平滑肌细胞松弛和血管舒张。Beraprost sodium 具有促血管扩张,抗血小板和细胞保护作用,有望用于心血管疾病领域研究,如血栓闭塞性脉管炎和闭塞性动脉硬化。

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(Rac)-Beraprost sodium Chemical Structure

(Rac)-Beraprost sodium Chemical Structure

CAS No. : 88475-69-8

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Other Forms of (Rac)-Beraprost sodium:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(Rac)-Beraprost ((Rac)-ML 1229) sodium is a racemic isomer of Beraprost sodium (HY-13569A). Beraprost sodium is an orally active prostacyclin analog that inhibits the release of Ca2+ from intracellular storage sites by binding to prostacyclin membrane receptors (Prostaglandin Receptor), leading to relaxation of smooth muscle cells and vasodilation. Beraprost sodium has vasodilatory, antiplatelet, and cytoprotective effects, making it promising for research in the field of cardiovascular diseases, such as thromboangiitis obliterans and atherosclerosis[1][2].

分子量

420.47

Formula

C24H29NaO5

CAS 号
性状

固体

中文名称

贝前列腺素钠

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

(Rac)-Beraprost sodium 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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