2. Metabolic Enzyme/Protease
  3. Farnesyl Transferase
  4. (Rac)-Lonafarnib

(Rac)-Lonafarnib  (Synonyms: Sch66336 racemate)

目录号: HY-15136B
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摩尔计算器

(Rac)-Lonafarnib (Sch66336 racemate) 是 Lonafarnib 的外消旋体。Lonafarnib 是一种有效的，具有口服活性的法尼基蛋白转移酶 (FPTase) 抑制剂，作用于 H-ras，K-ras 和 N-ras，IC50 分别为 1.9 nM，5.2 nM 和 2.8 nM。Lonafarnib 具有抗肝炎三角洲病毒 (HDV) 的活性

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(Rac)-Lonafarnib Chemical Structure

(Rac)-Lonafarnib Chemical Structure

CAS No. : 193275-86-4

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Other Forms of (Rac)-Lonafarnib:

(Rac)-Lonafarnib 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(Rac)-Lonafarnib (Sch66336 racemate) is the racemate of Lonafarnib. Lonafarnib is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities[1].

分子量

638.82

Formula

C27H31Br2ClN4O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(Rac)-Lonafarnib 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Rac)-Lonafarnib193275-86-4Sch66336Sch 66336Sch-66336Farnesyl TransferaseFtaseInhibitorinhibitorinhibit

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