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  3. (Rac)-PD0299685

(Rac)-PD0299685 是一种 Ca(2+) 通道 α2δ 配体,在一项随机、双盲、安慰剂对照的 IIa 期研究中,该配体被研究用于缓解间质性膀胱炎疼痛。与安慰剂相比,60 毫克剂量的 (Rac)-PD0299685 显示出每日最严重疼痛严重程度评分在临床上显著降低。(Rac)-PD0299685 也是一种有效的电压依赖性钙通道抑制剂,可用于研究视网膜相关疾病。

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(Rac)-PD0299685 Chemical Structure

(Rac)-PD0299685 Chemical Structure

CAS No. : 313651-02-4

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  • 参考文献

生物活性

(Rac)-PD0299685 is a Ca(2+) channel α2δ ligand that was investigated for relieving interstitial cystitis pain in a randomized, double-blind, placebo-controlled phase IIa study. (Rac)-PD0299685 demonstrated a clinically significant reduction in daily worst pain severity scores at the 60 mg dose compared to placebo. (Rac)-PD0299685 is also a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.

分子量

187.28

Formula

C10H21NO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

(Rac)-PD0299685 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(Rac)-PD0299685
目录号:
HY-169115A
需求量: