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Radamide是一种Grp94的抑制剂,具有抗迁移活性。Radamide被用于抑制与Grp94相关的疾病,如青光眼、癌症转移和多发性骨髓瘤。Radamide通过作用于Grp94的特殊结构,展现出选择性抑制活性。Radamide的衍生物在改进的结构活性关系研究中表现出更好的效能和选择性。

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Radamide Chemical Structure

Radamide Chemical Structure

CAS No. : 1166398-85-1

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生物活性

Radamide is an inhibitor of Grp94 with anti-migratory activity. Radamide is used to inhibit Grp94-related diseases such as glaucoma, cancer metastasis, and multiple myeloma. Radamide exhibits selective inhibitory activity by acting on the specific structure of Grp94. Radamide derivatives show better potency and selectivity in improved structure-activity relationship studies[1].

分子量

411.79

Formula

C18H18ClNO8

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Radamide
目录号:
HY-124221
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