2. Immunology/Inflammation
  3. Complement System
  4. Ravulizumab

Ravulizumab  (Synonyms: 雷夫利珠单抗; ALXN1210)

目录号: HY-P99365 纯度: 95.57%
COA 技术支持

Ravulizumab (ALXN1210) 是一种人源化单克隆抗体，它以高亲和力特异性结合人补体蛋白 C5。Ravulizumab 可用于阵发性睡眠性血红蛋白尿症、非典型溶血性尿毒症综合征和重症肌无力的研究。

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CAS No. : 1803171-55-2

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥7500
In-stock
10 mg ￥10056
In-stock
25 mg ￥14760
In-stock
50 mg ￥20040
In-stock
100 mg ￥27120
In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Customer Review

Ravulizumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ravulizumab (ALXN1210) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis[1].

同型

Human IgG4 kappa
推荐同型对照抗体
种属

Humanized
IC50 & Target

complement protein C5[1]
体外研究
(In Vitro)

Ravulizumab 与 C5 高亲和力结合并抑制 C5a 和 C5b 的形成，从而防止免疫激活和溶血[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ravulizumab 相关抗体:
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

雷夫利珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG2-G4-kappa
Biological Activity
  • Immobilized Complement C5/C5a Protein, Human can bind Ravulizumab. The EC50 for this effect is 115.5 ng/mL.
纯度 & 产品资料
参考文献

Ravulizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ravulizumab1803171-55-2ALXN1210雷夫利珠单抗ALXN 1210ALXN-1210Complement Systemcomplement proteinC5paroxysmal nocturnal hemoglobinuriaatypical hemolytic uremic syndromemyasthenia gravisInhibitorinhibitorinhibit

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