ACP5 蛋白, Mouse (HEK293, His)

The ACP5 protein may have a crucial role in bone resorption, particularly in the enzymatic activities involved in breaking down bone tissue. ACP5 is linked to the osteoclastic trap, which has higher affinity for nucleotide tri- and diphosphates. Understanding ACP5's mechanisms in bone resorption and its interactions with nucleotide substrates could offer insights into its role in maintaining bone health. ACP5 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ACP5 protein, expressed by HEK293 , with C-His labeled tag. The total length of ACP5 Protein, Mouse (HEK293, His) is 305 a.a., with molecular weight of ~35.8-38 kDa.

ACP5 蛋白可能在骨吸收过程中发挥至关重要的作用，表明它参与了骨组织分解的复杂机制。具体来说，ACP5 与破骨细胞陷阱相关，与其他底物相比，ACP5 对三磷酸和二磷酸核苷酸具有更高的亲和力。这表明 ACP5 与促进骨基质降解的酶活性有着复杂的联系，可能影响骨重塑的调节。进一步探索 ACP5 在骨吸收中发挥作用的具体机制及其与核苷酸底物的相互作用，可以为了解其在维持骨稳态中的作用以及对骨骼健康的潜在影响提供有价值的见解。

Measured by its ability to cleave a substrate, p-Nitrophenyl phosphate (pNPP). The specific activity is 78579.56 pmol/min/μg.

Mouse

HEK293

C-His

Q05117 (A23-P327)

11433  [NCBI]

APTPTLRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQTMGADFIMSLGDNFYFTGVHDASDKRFQETFEDVFSDRALRNIPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPYYRLRFKIPRTNITVAIFMLDTVMLCGNSDDFASQQPKMPRDLGVARTQLSWLKKQLAAAKEDYVLVAGHYPIWSIAEHGPTRCLVKNLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSVRHQRKVPNGYLRFHYGSEDSLGGFTHVEISPKEMTIIYVEASGKSLFKTSLPRRPRP

Approximately 35.8-38 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.