ADTRP 蛋白, Human (Cell-Free, His, Myc)

ADTRP protein exhibits specialized enzymatic activity, specifically hydrolyzing bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), with a notable preference for branched FAHFAs. This unique function distinguishes ADTRP, as it does not hydrolyze other major lipid classes. Moreover, ADTRP regulates endothelial cells, influencing TFPI expression and cell-associated anticoagulant activity, observed in in vitro settings. ADTRP Protein, Human (Cell-Free, His, Myc) is the recombinant human-derived ADTRP protein, expressed by E. coli Cell-free , with N-10*His, C-Myc labeled tag. The total length of ADTRP Protein, Human (Cell-Free, His, Myc) is 230 a.a., with molecular weight of 31.8 kDa.

ADTRP 蛋白表现出特殊的酶功能，特别是水解羟基脂肪酸的生物活性脂肪酸酯 (FAHFA)，并且对远离羧酸根头基的 FAHFAs 表现出明显的偏好。这种独特的酶活性使 ADTRP 与众不同，因为它不会水解其他主要类别的脂质。此外，如体外环境中观察到的，ADTRP 通过影响抑制剂 TFPI 的表达和细胞相关抗凝活性，在内皮细胞中发挥调节作用。

Human

E. coli Cell-free

N-10*His;C-Myc

Q96IZ2 (M1-K230)

84830

MTKTSTCIYHFLVLSWYTFLNYYISQEGKDEVKPKILANGARWKYMTLLNLLLQTIFYGVTCLDDVLKRTKGGKDIKFLTAFRDLLFTTLAFPVSTFVFLAFWILFLYNRDLIYPKVLDTVIPVWLNHAMHTFIFPITLAEVVLRPHSYPSKKTGLTLLAAASIAYISRILWLYFETGTWVYPVFAKLSLLGLAAFFSLSYVFIASIYLLGEKLNHWKWGDMRQPRKKRK

31.8 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.