1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Peptide Hormone & Neuropeptides
  4. AGRP 蛋白, Rhesus Macaque (HEK293, Fc)

AGRP 蛋白, Rhesus Macaque (HEK293, Fc)

目录号: HY-P75566
产品使用指南 技术支持

AGRP 蛋白是一种 α-黑素细胞刺激激素拮抗剂,通过中央黑素皮质素系统调节摄食行为维持体重平衡。AGRP 抑制由刺激下丘脑和肾上腺内的黑素皮质素受体介导的 cAMP 产生。AGRP 可作为 MC3RMC4R 的抑制剂。AGRP 蛋白, Rhesus Macaque (HEK293, Fc) 是重组的 AGRP 蛋白,由 HEK293 表达,带有 N-mFc 标签。AGRP 蛋白, Rhesus Macaque (HEK293, Fc) 全长 50 个氨基酸,分子量约为 ~32.3 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

AGRP protein is an alpha-melanocyte stimulating hormone antagonist that regulates feeding behavior through the central melanocortin system to maintain body weight balance. AGRP inhibits cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal glands. AGRP can act as an inhibitor of MC3R and MC4R. AGRP Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived AGRP protein, expressed by HEK293 , with N-mFc labeled tag. The total length of AGRP Protein, Rhesus Macaque (HEK293, Fc) is 50 a.a., with molecular weight of ~32.3 kDa.

研究背景

AGRP 蛋白在体重平衡中起着至关重要的作用,并通过中央黑素皮质素系统调节摄食行为。AGRP 是一种 α-黑素细胞刺激激素拮抗剂,AGRP 抑制由刺激下丘脑和肾上腺内的黑素皮质素受体介导的 cAMP 产生。AGRP 可作为 MC3RMC4R 的逆激动剂,抑制它们的组成活性。AGRP 以抑制依赖的方式促进 MC3RMC4R 的内吞作用。

种属

Rhesus Macaque

表达系统

HEK293

标签

N-mFc

蛋白编号

XP_001091740 (S83-T132)

基因 ID
蛋白结构
N-term
mFc
AGRP (S83-T132)
Accession # XP_001091740
C-term
同用名
Agouti-related protein; AGRP; AGRT; ART
分子量

Approximately 32.3 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

AGRP Protein, Rhesus Macaque (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
AGRP Protein, Rhesus Macaque (HEK293, Fc)
目录号:
HY-P75566
需求量: