1. 重组蛋白
  2. Enzymes & Regulators
  3. Oxidoreductases (EC 1)
  4. ALDH7A1 蛋白, Human (His)

ALDH7A1 蛋白, Human (His)

目录号: HY-P76140
COA 产品使用指南

ALDH7A1 是一种多功能酶,在介导保护作用中发挥着至关重要的作用。它将甜菜碱醛代谢为甜菜碱,作为重要的细胞渗透剂和甲基供体。此外,ALDH7A1 通过代谢脂质过氧化产生的各种醛来保护细胞免受氧化应激。此外,它还参与赖氨酸分解代谢。ALDH7A1 蛋白, Human (His) 是重组的 ALDH7A1 蛋白,由 E. coli 表达,带有 N-His 标签。ALDH7A1 蛋白, Human (His) 全长 510 个氨基酸,分子量约为 ~56 KDa。

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规格 价格 是否有货 数量
50 μg ¥7150 In-stock
100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

ALDH7A1, a multifunctional enzyme, plays a crucial role in mediating protective effects. It metabolizes betaine aldehyde into betaine, acting as a significant cellular osmolyte and methyl donor. Furthermore, ALDH7A1 safeguards cells from oxidative stress by metabolizing various aldehydes derived from lipid peroxidation. Additionally, it participates in lysine catabolism. ALDH7A1 Protein, Human (His) is the recombinant human-derived ALDH7A1 protein, expressed by E. coli , with N-His labeled tag. The total length of ALDH7A1 Protein, Human (His) is 510 a.a., with molecular weight of ~56 KDa.

研究背景

ALDH7A1 是一种多功能酶,在介导细胞内的基本保护作用方面发挥着至关重要的作用。它催化甜菜碱醛转化为甜菜碱,作为重要的细胞渗透剂和甲基供体。值得注意的是,ALDH7A1 通过代谢脂质过氧化产生的各种醛,充当对抗氧化应激的保护盾。此外,该酶积极参与赖氨酸分解代谢,有助于更广泛的代谢过程。通过其多方面的活性,ALDH7A1 成为细胞防御机制和基本代谢途径的关键参与者。

生物活性

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

种属

Human

表达系统

E. coli

标签

N-His

蛋白编号

P49419-2 (S2-Q511)

基因 ID

501  [NCBI]

蛋白结构
N-term
His
ALDH7A1 (S2-Q511)
Accession # P49419-2
C-term
同用名
Alpha-aminoadipic semialdehyde dehydrogenase; Alpha-AASA dehydrogenase; Antiquitin-1; P6c dehydrogenase; ATQ1
氨基酸序列

STLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ

分子量

Approximately 56 kDa.

纯度

Greater than 90% as determined by reducing SDS-PAGE

性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 500 mM NaCl, 20% Glycerol, 5% Trehalose, 5% Mannitol, 0.01% Tween-80.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

ALDH7A1 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
ALDH7A1 Protein, Human (His)
目录号:
HY-P76140
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