Animal-Free CXCL16 蛋白, Mouse (His)

The CXCL16 protein has multiple functions, inducing chemotactic responses and initiating calcium mobilization. As a ligand, it binds to CXCR6/Bonzo and promotes cell signaling. Animal-Free CXCL16 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeCXCL16 protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free CXCL16 Protein, Mouse (His) is 175 a.a., with molecular weight of ~10.74 kDa.

CXCL16 蛋白表现出多方面的功能，包括诱导强大的趋化反应和启动钙动员。作为配体，它与 CXCR6/Bonzo 结合，从而促进细胞信号传导过程。除了作为趋化因子的作用外，CXCL16 还可以作为巨噬细胞上的清道夫受体，对氧化低密度脂蛋白 (OxLDL) 显示出特定的亲和力。这种相互作用表明它可能参与病理生理过程，特别是动脉粥样硬化形成，其中巨噬细胞对 OxLDL 的识别和清除起着至关重要的作用。CXCL16 的多种活性凸显了其多功能性，并强调了其对细胞反应和病理状况的潜在影响。

Measure by its ability to chemoattract BaF3 cells transfected with mouse CXCR6. The ED₅₀ for this effect is <3 ng/mL.

Mouse

E. coli

N-His

Q8BSU2 (N27-W201)

66102  [NCBI]

NQGSVAGSCSCDRTISSGTQIPQGTLDHIRKYLKAFHRCPFFIRFQLQSKSVCGGSQDQWVRELVDCFERKECGTGHGKSFHHQKHLP

Approximately 10.74 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 7.4, trehalose.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.