ApoA-IV 蛋白, Mouse (P.pastoris, His)

ApoA-IV Protein plays a vital role in lipid metabolism, influencing chylomicron and VLDL secretion and catabolism. It efficiently activates lipoprotein lipase with ApoC-II and serves as a potent activator of LCAT. As a component of HDL and chylomicrons, ApoA-IV is integral to cholesterol transport and metabolism. Structurally, the protein forms homodimers, reflecting its crucial role in lipid-related processes. ApoA-IV Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived ApoA-IV protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of ApoA-IV Protein, Mouse (P.pastoris, His) is 375 a.a., with molecular weight of ~45.0 kDa.

ApoA-IV 蛋白参与脂质代谢的各个方面，在乳糜微粒和极低密度脂蛋白 (VLDL) 的分泌和分解代谢中发挥潜在作用。它对于 ApoC-II 有效激活脂蛋白脂肪酶至关重要，并且是卵磷脂胆固醇酰基转移酶 (LCAT) 的有效激活剂。ApoA-IV 作为高密度脂蛋白 (HDL) 和乳糜微粒的重要组成部分出现，凸显了它参与胆固醇转运和代谢。在结构上，该蛋白质形成同二聚体，表明其在这些关键的脂质相关过程中的分子排列。

Mouse

P. pastoris

N-6*His

P06728 (E21-S395)

11808  [NCBI]

EVTSDQVANVVWDYFTQLSNNAKEAVEQFQKTDVTQQLSTLFQDKLGDASTYADGVHNKLVPFVVQLSGHLAQETERVKEEIKKELEDLRDRMMPHANKVTQTFGENMQKLQEHLKPYAVDLQDQINTQTQEMKLQLTPYIQRMQTTIKENVDNLHTSMMPLATNLKDKFNRNMEELKGHLTPRANELKATIDQNLEDLRRSLAPLTVGVQEKLNHQMEGLAFQMKKNAEELQTKVSAKIDQLQKNLAPLVEDVQSKVKGNTEGLQKSLEDLNRQLEQQVEEFRRTVEPMGEMFNKALVQQLEQFRQQLGPNSGEVESHLSFLEKSLREKVNSFMSTLEKKGSPDQPQALPLPEQAQEQAQEQAQEQVQPKPLES

Approximately 45.0 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm sterile filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.