Apolipoprotein M/APOM 蛋白, Mouse (P.pastoris, His)

Apolipoprotein M (APOM) is likely involved in lipid transport, binding various molecules, including sphingosine-1-phosphate, myristic acid, palmitic acid, stearic acid, retinol, all-trans-retinoic acid, and 9-cis-retinoic acid. Interacting with LRP2, APOM undergoes renal uptake facilitated by LRP2, followed by lysosomal degradation. This suggests APOM's role in mediating dynamic lipid and retinoid metabolism processes within the body. Apolipoprotein M/APOM Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Apolipoprotein M/APOM, expressed by P. pastoris , with N-His labeled tag.

载脂蛋白 M (APOM) 可能与脂质转运有关，显示出结合各种分子的能力，包括 1-磷酸鞘氨醇、肉豆蔻酸、棕榈酸和硬脂酸，以及视黄醇、全反式视黄酸和9-顺式-视黄酸。通过其相互作用，APOM 已被证明可以与 LRP2 结合，从而 LRP2 促进 APOM 的肾脏摄取，导致随后的溶酶体降解。这表明 APOM 在介导体内脂质和类视黄醇代谢的动态过程中发挥着作用。

Mouse

P. pastoris

N-His

Q9Z1R3 (M1-K190)

55938  [NCBI]

MFHQVWAALLSLYGLLFNSMNQCPEHSQLTALGMDDTETPEPHLGLWYFIAGAASTTEELATFDPVDNIVFNMAAGSAPRQLQLRATIRTKSGVCVPRKWTYRLTEGKGNMELRTEGRPDMKTDLFSSSCPGGIMLKETGQGYQRFLLYNRSPHPPEKCVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK

Approximately 30.0 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from 0.22 μm filtered solution in PBS, 3% Trehalose, pH 7.4.

<1.0 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.