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  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. Arylsulfatase B/ARSB 蛋白, Human (His-SUMO)

Arylsulfatase B/ARSB 蛋白, Human (His-SUMO)

目录号: HY-P702611
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芳基硫酸酯酶 B (ARSB) 蛋白通过去除 4-硫酸软骨素 (C4S) 中的硫酸基团从而指导其降解,对于细胞稳态至关重要。其酶活性影响结肠上皮细胞的粘附、迁移和侵袭。Arylsulfatase B/ARSB 蛋白, Human (His-SUMO) 是重组的 芳基硫酸酯酶B/ARSB,由 E. coli Cell-free 表达,带有 N-SUMO, N-6*His 标签。Arylsulfatase B/ARSB 蛋白, Human (His-SUMO) 全长 497 个氨基酸

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描述

The arylsulfatase B (ARSB) protein is critical for cellular homeostasis by removing the sulfate group from chondroitin 4-sulfate (C4S), thereby directing its degradation. Its enzymatic activity affects the adhesion, migration and invasion of colon epithelial cells. Arylsulfatase B/ARSB Protein, Human (His-SUMO) is the recombinant human-derived Arylsulfatase B/ARSB, expressed by E. coli Cell-free , with N-SUMO, N-6*His labeled tag. The total length of Arylsulfatase B/ARSB Protein, Human (His-SUMO) is 497 a.a.,

研究背景

芳基硫酸酯酶 B (ARSB) 蛋白通过去除 4-硫酸软骨素 (C4S) 中的硫酸基团并协调其降解,在维持细胞稳态中发挥着至关重要的作用。这种酶活性将其影响扩展到各种细胞过程,包括结肠上皮内细胞粘附、迁移和侵袭的调节。除了参与胃肠系统外,ARSB 还成为中枢神经系统的关键调节剂,调节神经突生长和神经元可塑性。这种调节功能是通过控制硫酸糖胺聚糖和神经聚糖水平来执行的,突出了 ARSB 在维持不同组织中细胞的结构和功能完整性方面的多方面影响。

种属

Human

表达系统

E. coli Cell-free

标签

N-SUMO;N-6*His

蛋白编号

P15848-1 (S37-M533)

基因 ID

411

同用名
Arylsulfatase B; ASB; N-acetylgActosamine-4-sulfatase; G4S
分子量

72.0 kDa

纯度

Greater than 90 % as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Arylsulfatase B/ARSB Protein, Human (His-SUMO) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Arylsulfatase B/ARSB Protein, Human (His-SUMO)
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HY-P702611
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