ATP5J2 蛋白, Human (Cell-Free, His)

ATP5J2 protein is a component of mitochondrial membrane ATP synthase (complex V), which uses the proton gradient established by the respiratory chain electron transport complex to help ADP synthesize ATP. ATP5J2 is located in the F(0) domain as a small subunit and cooperates with subunit a in the membrane. ATP5J2 Protein, Human (Cell-Free, His) is the recombinant human-derived ATP5J2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of ATP5J2 Protein, Human (Cell-Free, His) is 94 a.a., with molecular weight of 12.4 kDa.

ATP5J2 蛋白是线粒体膜 ATP 合酶的一部分，也称为复合体 V，负责在呼吸链电子传递复合体产生的质子梯度存在下从 ADP 合成 ATP。F 型 ATP 酶分为两个结构域：F(1)（包含膜外催化核心）和 F(0)（包含膜质子通道）。这些域通过中央茎和外围茎连接。在催化过程中，F(1) 催化结构域中的 ATP 合成通过涉及中心茎亚基的旋转机制与质子易位协调。ATP5J2 专门位于 F(0) 结构域内，与膜中的亚基 a 一起充当次要亚基。整个 F 型 ATP 酶复合物包括 CF(1)（催化核心）和 CF(0)（膜质子通道），特定的亚基有助于其独特的功能。ATP5J2 是较大 ATP 合酶复合体的一个组成部分，与各种其他亚基协作促进 ATP 合成。

Human

E. coli Cell-free

N-10*His

P56134 (M1-H94)

9551

MASVGECPAPVPVKDKKLLEVKLGELPSWILMRDFSPSGIFGAFQRGYYRYYNKYINVKKGSISGITMVLACYVLFSYSFSYKHLKHERLRKYH

12.4 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.