2. 重组蛋白
  3. Immune Checkpoint Proteins CD Antigens Biotinylated Proteins
  4. Inhibitory Checkpoint Molecules Stimulatory Immune Checkpoint Molecules T Cell CD Proteins B Cell CD Proteins NK Cell CD Proteins Macrophage CD Proteins Monocyte CD Proteins Dendritic Cell CD Proteins Endothelial cell CD Proteins
  5. B7-2/CD86
  6. B7-2/CD86 蛋白, Human (HEK293, His-Avi)

B7-2/CD86 蛋白, Human (HEK293, His-Avi)

目录号: HY-P78383
产品使用指南

B7-2/CD86 蛋白通过破坏 CD86 簇形成、调节 T 细胞反应和影响免疫激活来负调节 T 细胞激活。B7-2/CD86 蛋白, Human (HEK293, His-Avi) 是重组的 B7-2/CD86 蛋白，由 HEK293 表达，带有 C-Avi, C-His 标签。B7-2/CD86 蛋白, Human (HEK293, His-Avi) 全长 222 个氨基酸，分子量为 55-70 kDa。

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描述

B7-2/CD86 protein negatively regulates T-cell activation by disrupting CD86 cluster formation, modulating the T-cell response, and influencing immune activation. B7-2/CD86 Protein, Human (HEK293, His-Avi) is the recombinant human-derived B7-2/CD86 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of B7-2/CD86 Protein, Human (HEK293, His-Avi) is 222 a.a., with molecular weight of 55-70 kDa.
研究背景

B7-2/CD86 蛋白通过破坏 CD86 簇的形成，充当 T 细胞激活的负调节因子。通过这种干扰，它可以调节 T 细胞反应并在调节免疫激活中发挥作用。
种属

Human
表达系统

HEK293
标签

C-Avi;C-His
蛋白编号

P42081 (L26-P247)
基因 ID

942  [NCBI]
蛋白结构
N-term
B7-2 (L26-P247)
Accession # P42081
His-Avi
C-term
同用名
CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2
分子量

55-70 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

B7-2/CD86 Protein, Human (HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
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