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  3. BTBD9 蛋白, Human (Sf9, His, StrepⅡ)

BTBD9 蛋白, Human (Sf9, His, StrepⅡ)

目录号: HY-P701539
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BTBD9 蛋白参与调节小鼠海马突触可塑性以及学习记忆。BTBD9 参与发育中的黑腹果蝇的四肢形成和细胞命运的决定。BTBD9 也是不宁腿综合征 (RLS) 的遗传危险因素。BTBD9 通过调节胰岛素/胰岛素样生长因子信号通路减轻锰诱导的秀丽隐杆线虫氧化应激和神经毒性。BTBD9 蛋白, Human (Sf9, His, Strep) 是重组的 BTBD9 蛋白,由 Sf9 insect cells 表达,带有 N-Strep, N-8*His 标签。BTBD9 蛋白, Human (Sf9, His, Strep) 全长 611 个氨基酸。

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描述

The BTBD9 protein is invovled in regulating hippocampal synaptic plasticity and learning and memory in mice. BTBD9 is involved in formation of the limbs and cell fate determination in the developing Drosophila melanogaster. BTBD9 is also a genetic risk factor of Restless legs syndrome (RLS). BTBD9 alleviates Mn-induced oxidative stress and neurotoxicity in Caenorhabditis elegans. via regulation of insulin/insulin-like growth factor signaling pathway[1][2][3]. BTBD9 Protein, Human (Sf9, His, Strep) is the recombinant human-derived BTBD9 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of BTBD9 Protein, Human (Sf9, His, Strep) is 611 a.a., .

研究背景

BTBD9 蛋白包含 BTB/POZ 结构域和 BACK 结构域。BTBD9 广泛表达于小鼠中枢神经系统,如丘脑、下丘脑等。因此,BTBD9参与调节海马突触可塑性和学习记忆。BTBD9 还参与发育中的黑腹果蝇的四肢形成和细胞命运决定[1][2]。此外,BTBD9 也是不宁腿综合征 (RLS) 的遗传危险因子。Btbd9 敲除小鼠表现出运动不安、睡眠中断、感觉知觉和血清铁水平改变以及恐惧记忆增强。BTBD9 通过调节胰岛素/胰岛素样生长因子信号通路来减轻锰诱导的秀丽隐杆线虫氧化应激和神经毒性[3]

种属

Human

表达系统

Sf9 insect cells

标签

N-StrepⅡ;N-8*His

蛋白编号

Q96Q07 (S2-Q612)

基因 ID

114781

蛋白结构
N-term
8*His-StrepⅡ
BTBD9 (S2-Q612)
Accession # Q96Q07
C-term
同用名
BTBD9; BTB/POZ domain-containing protein 9
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

BTBD9 Protein, Human (Sf9, His, StrepⅡ) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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BTBD9 Protein, Human (Sf9, His, StrepⅡ)
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