BTN1A1 蛋白, Human (HEK293, Fc)

BTN1A1 Protein is implicated in milk-fat droplet secretion and may serve as a membrane-associated receptor in lactation processes. Additionally, it exhibits immune-regulatory functions, inhibiting T-cell proliferation and modulating cytokine secretion. BTN1A1's association with xanthine dehydrogenase/oxidase suggests diverse cellular functions, inviting further exploration into its role in various biological pathways. BTN1A1 Protein, Human (HEK293, Fc) is the recombinant human-derived BTN1A1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of BTN1A1 Protein, Human (HEK293, Fc) is 216 a.a., with molecular weight of 60-80 kDa.

BTN1A1 蛋白被认为在乳脂滴的分泌中发挥作用，表明它可能参与与哺乳相关的复杂过程。此外，如相似性分析所示，它可能充当特定的膜相关受体，促进细胞质液滴与顶端质膜的结合。此外，BTN1A1对抗CD3抗体激活的CD4和CD8 T细胞增殖具有抑制作用，影响T细胞代谢，调节IL2和IFNG的分泌，凸显了其在免疫调节中的潜在作用。值得注意的是，BTN1A1 似乎还与黄嘌呤脱氢酶/氧化酶相关，这引发了关于其多样化细胞功能以及在各种生物途径中的潜在影响的进一步问题。

Human

HEK293

C-hFc

Q13410 (A27-R242)

696  [NCBI]

APFDVIGPPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFFREDGSYEEALVHLKVAALGSDPHISMQVQENGEICLECTSVGWYPEPQVQWRTSKGEKFPSTSESRNPDEEGLFTVAASVIIRDTSAKNVSCYIQNLLLGQEKKVEISIPASSLPR

60-80 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.