1. 重组蛋白
  2. Immune Checkpoint Proteins Biotinylated Proteins
  3. Butyrophilins
  4. BTN2A2
  5. BTN2A2 蛋白, Human (Biotinylated, HEK293, Fc-Avi)

BTN2A2 蛋白, Human (Biotinylated, HEK293, Fc-Avi)

目录号: HY-P72344
产品使用指南

BTN2A2 蛋白抑制抗 CD3 抗体激活的 CD4 和 CD8 T 细胞增殖。它调节 T 细胞代谢,抑制 IL2 和 IFNG 细胞因子的分泌。BTN2A2 在免疫反应调节中发挥着关键作用,通过限制 T 细胞激活和效应器功能来维持免疫稳态。BTN2A2 蛋白, Human (Biotinylated, HEK293, Fc-Avi) 是重组的 BTN2A2 蛋白,由 HEK293 表达,带有 C-Avi, C-hFc 标签。BTN2A2 蛋白, Human (Biotinylated, HEK293, Fc-Avi) 全长 205 个氨基酸,分子量为 55-80 kDa。

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SPR 检测服务   重组蛋白定制服务

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

BTN2A2 protein inhibits CD4 and CD8 T-cell proliferation activated by anti-CD3 antibodies. It regulates T-cell metabolism, suppressing IL2 and IFNG cytokine secretion. BTN2A2 plays a pivotal role in immune response modulation, maintaining immune homeostasis by limiting T-cell activation and effector functions. BTN2A2 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived BTN2A2 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of BTN2A2 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 205 a.a., with molecular weight of 55-80 kDa.

研究背景

BTN2A2 蛋白起到抑制剂的作用,阻止被抗 CD3 抗体激活的 CD4 和 CD8 T 细胞的增殖。此外,它还对 T 细胞代谢进行调节控制,并抑制细胞因子 IL2 和 IFNG 的分泌。这种抑制反映了 BTN2A2 通过限制 T 细胞的激活和效应功能来调节免疫反应和维持免疫稳态的关键作用。

种属

Human

表达系统

HEK293

标签

C-Avi;C-hFc

蛋白编号

Q8WVV5 (Q33-V237)

基因 ID
蛋白结构
N-term
BTN2A2 (Q33-V237)
Accession # Q8WVV5
hFc-Avi
C-term
同用名
Butyrophilin subfamily 2 member A2; BTN2A2
氨基酸序列

QFTVVGPANPILAMVGENTTLRCHLSPEKNAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEYRGRITFVSKDINRGSVALVIHNVTAQENGIYRCYFQEGRSYDEAILRLVVAGLGSKPLIEIKAQEDGSIWLECISGGWYPEPLTVWRDPYGEVVPALKEVSIADADGLFMVTTAVIIRDKYVRNVSCSVNNTLLGQEKETV

分子量

55-80 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

BTN2A2 Protein, Human (Biotinylated, HEK293, Fc-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
BTN2A2 Protein, Human (Biotinylated, HEK293, Fc-Avi)
目录号:
HY-P72344
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