Carboxypeptidase B1/CPB1 蛋白, Mouse (HEK293, His)

Carboxypeptidase B1/CPB1 protein is part of the PDGF/VEGF growth factor family and has the same structural and functional characteristics as proteins that affect cell growth, proliferation and angiogenesis. This family is critical for mediating endothelial cell responses and promoting blood vessel formation, including VEGF-C, which is involved in lymphangiogenesis. Carboxypeptidase B1/CPB1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carboxypeptidase B1/CPB1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carboxypeptidase B1/CPB1 Protein, Mouse (HEK293, His) is 400 a.a., with molecular weight of 43-45 kDa.

VEGF-C 蛋白属于 PDGF/VEGF 生长因子家族。作为该家族的一员，它与参与细胞生长、增殖和血管生成调节的其他蛋白质具有相同的结构和功能特征。PDGF/VEGF家族以其在介导血管内皮细胞反应和促进血管形成中的关键作用而闻名。特别是，VEGF-C 与淋巴管生成有关，在淋巴管的发育和维护中发挥着关键作用。PDGF/VEGF 生长因子家族的分类表明 VEGF-C 可能有助于协调与血管和淋巴系统相关的生理和病理过程的信号通路。

Measured by its ability to cleave a colorimetric peptide substrate, Hippuryl-Arg. The specific activity is 17715.8 pmoL/min/µg.

Mouse

HEK293

C-His

B2RS76 (S16-Y415)

76703  [NCBI]

SEENFDGNRVFRVSVHDEDDVSLIQELANTKQIDFWKPDSATQVKPLTTVDFHVKAEDVVDVENFLEENEVLYEVLISNVKHILESQFDSHTRASGHSYTKYNNWETIEAWIQQVANDNPDLVSKRVIGTTFEGRNMYVLKIGKDRPNKPAFFIDCGFHAREWISPAFCQWFVREAVRTYKQEIHMKRLLDELDFYVLPVVNIDGYVYTWAKDRMWRKTRSTTAGSSCFGVDPNRNFDAGWCEVGASRSPCSDTYCGPTPESEKETKALADFIRQNLSSIKAYLTVHSYSQMMLYPYSYDYKLPENYEELNALVKGAAKELSTLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGFFGFLLPESQIRQTCEETMLAVKYIANYVLEHPY

Approximately 45 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM Nacl, PH 6.5.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.