CCN2/CTGF 蛋白, Human (HEK293, His)

CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human (HEK293, His) is the recombinant human-derived CCN2/CTGF protein, expressed by HEK293 , with C-His labeled tag. The total length of CCN2/CTGF Protein, Human (HEK293, His) is 323 a.a., with molecular weight of 45-60 kDa.

CCN2/CTGF（结缔组织生长因子）是一种主要由血管内皮细胞产生的蛋白质。它在各种细胞过程中发挥着重要作用。它的主要功能之一是吸引和刺激软骨细胞的增殖和分化，软骨细胞是参与软骨形成的细胞。此外，CCN2/CTGF 介导各种细胞类型的细胞粘附，包括成纤维细胞、肌成纤维细胞、内皮细胞和上皮细胞。这种粘附取决于肝素（一种多糖）和二价阳离子（例如钙或镁）的存在。此外，CCN2/CTGF 还能增强成纤维细胞生长因子（参与细胞生长和修复的蛋白质）诱导的 DNA 合成。总体而言，CCN2/CTGF 是一种重要的蛋白质，可调节软骨细胞功能、细胞粘附和 DNA 合成等细胞过程，有助于结缔组织的发育和维护。

1.Immobilized Human CTGF, His Tag at 0.5 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-CTGF Antibody, hFc Tag with the EC₅₀ of ≤ 8 ng/mL determined by ELISA. 2.Immobilized Human CTGF, His Tag at 1 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-CTGF Antibody, hFc Tag with the EC₅₀ of ≤7 ng/mL determined by ELISA.

Human

HEK293

C-His

Q5M8T4 (Q27-A349)

1490  [NCBI]

45-60 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.