1. 重组蛋白
  2. CD Antigens
  3. T Cell CD Proteins Dendritic Cell CD Proteins
  4. CD1a
  5. CD1A 蛋白, Human (HEK293, His)

CD1A 蛋白, Human (HEK293, His)

目录号: HY-P77624
产品使用指南

CD1A 蛋白是一种关键的抗原呈递分子,可结合自身和非自身脂质和糖脂抗原,并将其呈递给自然杀伤 T 细胞上的 T 细胞受体。CD1A 作为 B2M(β-2-微球蛋白)异二聚体,在免疫监视和调节中发挥着核心作用。CD1A 蛋白, Human (HEK293, His) 是重组的 CD1A 蛋白,由 HEK293 表达,带有 C-His 标签。CD1A 蛋白, Human (HEK293, His) 全长 282 个氨基酸,分子量为 48-53 kDa。

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描述

The CD1A protein is a key antigen-presenting molecule that binds self and non-self lipid and glycolipid antigens and presents them to T cell receptors on natural killer T cells. CD1A, as a B2M (beta-2-microglobulin) heterodimer, plays a central role in immune surveillance and regulation. CD1A Protein, Human (HEK293, His) is the recombinant human-derived CD1A protein, expressed by HEK293 , with C-His labeled tag. The total length of CD1A Protein, Human (HEK293, His) is 282 a.a., with molecular weight of 48-53 kDa.

研究背景

CD1A 蛋白是一种关键的抗原呈递分子,具有结合自身和非自身脂质和糖脂抗原的独特能力,促进其呈递给自然杀伤 T 细胞上的 T 细胞受体。该蛋白与 B2M(β-2-微球蛋白)形成异二聚体,在免疫监视和调节中发挥着核心作用。它与 CD74 的相互作用进一步强调了它在免疫系统复杂机制中的重要性,强调了它在协调 T 细胞对不同抗原的反应中的作用。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

P06126 (D19-V300)

基因 ID

909  [NCBI]

蛋白结构
N-term
CD1A (D19-V300)
Accession # P06126
His
C-term
同用名
CD1a; CD1A; CD1; FCB6; HTA1; R4; T6
分子量

48-53 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CD1A Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD1A Protein, Human (HEK293, His)
目录号:
HY-P77624
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